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While it typically lasts longer than other side effects (about 7 weeks on average), it's usually manageable with proper hydration, gradual fiber increases, physical activity, and over-the-counter remedies if necessary

doi:10.1056/NEJMoa1607141 This study, part of the SUSTAIN-6 trial, investigated the cardiovascular effects of semaglutide in patients with type 2 diabetes and found a potential reduction in cardiovascular events, which might indirectly affect blood pressure